Journal article
Gastrulation in Drosophila melanogaster: Genetic control, cellular basis and biomechanics



Publication Details
Authors:
Gheisari, E.; Aakhte, M.; Müller, H.
Publication year:
2020
Journal:
Mechanisms of Development
Pages range:
103629
Volume number:
163
ISSN:
0925-4773

Abstract
Gastrulation is generally understood as the morphogenetic processes that result in the spatial organization of the blastomere into the three germ layers, ectoderm, mesoderm and endoderm. This review summarizes our current knowledge of the morphogenetic mechanisms in Drosophila gastrulation. In addition to the events that drive mesoderm invagination and germband elongation, we pay particular attention to other, less well-known mechanisms including midgut invagination, cephalic furrow formation, dorsal fold formation, and mesoderm layer formation. This review covers topics ranging from the identification and functional characterization of developmental and morphogenetic control genes to the analysis of the physical properties of cells and tissues and the control of cell and tissue mechanics of the morphogenetic movements in the gastrula.


Authors/Editors

Last updated on 2021-28-07 at 14:55